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Gastric MALT Lymphoma of the Superficial Type not Regressing after Helicobacter pylori Eradication, Report of a Case Johji Oda 1 , Touzou Hosoi 1 , Toshikuni Okada 1 1Department of Gastroenterology, Tokyo Metropolitan Tama Cancer Detection Center Keyword: 表層型胃MALTリンパ腫 , Helicobacter pylori , 除菌治療 pp.595-603
Published Date 2002/3/25
DOI https://doi.org/10.11477/mf.1403103499
  • Abstract
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 A 62-year-old woman underwent gastric mass survey and it was found that there was convergency and interruption of folds as well as an irregularly-shaped depression with the internal granules on the anterior wall of the angular part. She was followed up by a detailed examination. Endoscopy and x-ray showed that the lesion on the anterior wall of the angular part was characterized by narrow ditch-shaped erosions throughout its circumference and accompanied by whitish coating and roundish, even-sized granules. The lesion on the greater curvature of the upper body revealed an irregularly-shaped depression with internal reddish and small granules. The clinical diagnosis was MALT lymphoma. The biopsy specimen was also MALT lymphoma, compatible. Furthermore, rearranged bands of IG (H) JH were revealed by Southern blot analysis. Rapid urease test of the biopsy specimen was positive for Helicobacter pylori (H. pylori). Based on this data, the lesion was finally diagnosed as MALT lymphoma of the stomach and eradication therapy against H. pylori was performed. Clinical findings of the lesion on the anterior wall of the angular part improved and biopsy findings indicative of MALT lymphoma disappeared. However, in spite of the eradication therapy, endoscopic findings of the lesion on the greater curvature of the upper body showed no sign of improvement and the biopsy specimens were still compatible with MALT lymphoma. It was thus concluded that the H. pylori eradication therapy was ineffective.


Copyright © 2002, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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