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Japanese

Long-term Follow-up the Gastroduodenal Lesions of Crohn's Disease: Quantitative Analysis of the Endoscopic Findings Sadamune Hatakeyama 1 , Tuneyoshi Yao 1 , Toshiyuki Matsui 1 1Department of Gastroenterology, Fukuoka University Chikushi Hospital Keyword: Crohn病 , , 十二指腸病変 , 長期経過 pp.1239-1248
Published Date 1999/9/25
DOI https://doi.org/10.11477/mf.1403102817
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 Endoscopic findings on the gastroduodenal lesions of Crohn's disease are evaluated by assessing ulcerative and elevated lesions using original scores. Score of the gastroduodenal lesion of the initial endoscopic findings did not correlate with classification, activity index, and inflammatory findings, therefore extends of gastroduodenal and intestinal lesions did not seem to be mutually related. Six out of 286 cases of Crohn's disease were complicated with pyloric stenosis during the follow-up period. Cumulative rates of pyloric stenosis were 2.7% in 10 years after the initial symptoms and 3.1% in 10 years after diagnosis. Pyloric stenosis developed in comparatively rapid fashion with cobblestone-like appearance. Six cases of Crohn's disease with pyloric stenosis (stenosis group) were compared with 28 cases of Crohn's disease without pyloric stenosis that were followed for more than 10 years (non-stenosis group). Elevation score of the initial endoscopic pictures in the stenosis group was significantly higher than that in the non-stenosis group. This suggested that cases with advanced elevated lesion might have tendency to develop pyloric stenosis. Ulceration score of the initial endoscopic pictures was higher than that of the last endoscopic pictures. Ulcerative lesions like erosion and ulcer may not be progressive and may be composed of lesions associated with Crohn's disease and lesions caused by the same mechanism as the ordinary ulcer and erosion.


Copyright © 1999, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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