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Postoperative Course of Crohn's Disease Viewed from Radiographic and Endoscopic Findings Tsuneyoshi Yao 1 1Department of Internal Medicine, Fukuoka University Chikushi Hospital Keyword: Crohn病 , 術後経過 , 吻合部再発 , 広汎囲切除 , 多発アフタ pp.627-642
Published Date 1991/6/25
DOI https://doi.org/10.11477/mf.1403102556
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 Postoperative course of 39 patients with Crohn's disease was studied in a total of 48 operations. Those patients were diagnosed as having Crohn's disease and were treated at the First Department of Internal Medicine of Fukuoka University or at the Department of Internal Medicine of Fukuoka University Chikushi Hospital and were eventually operated on by Arima S M.D., one of the authors. The period of follow-up by radiography and endoscopy was 4.0±2.3 years.

 1) Recurrence rate observed by radiography and endoscopy was 79.2%.

 2) Approximately 90% of recurrence consisted of (i) recrudescence of remnant lesions of the small bowel (28.9%) and (ii) recurrence of the anastomotic site caused by multiple aphthous lesions (60.5%).

 3) Recurrence of longitudinal ulcers and cobblestoning remaining on the non-resected bowel was recognized in 11 of 13 patients.

 4) Recurrence caused by multiple aphthous lesions occurred four to nine months after operation.

 5) Recurrence by multiple aphthous lesions progressed to longitudinal ulcers and cobblestoning 4.3±2.8 years after operation, and further progressed to lesions having stenosis 6.0±2.0 years after operation.

 6) Newly developed lesions were recognized in the large bowel in approximately 30% of the follow-up cases. Those lesions mostly developed after small intestinal recurrence.

 From these results and with reference to the literature, concludsion is as follows:

 (i) An extensive resection to remove small lesions is not desirable.

 (ii) Reevaluation of operative procedures and reestimation of postoperative medical treatment such as home elemental diet are required.

 (iii) It is required to study the clinicopathological difference of the proximal site (mostly the small bowel) and the distal site (mostly the large bowel) of the anastomosis.


Copyright © 1991, Igaku-Shoin Ltd. All rights reserved.

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