雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Early Lesions of Ulcerative Colitis : Focused on Endoscopic Characteristics and Differential Diagnosis Kiyonori Kobayashi 1 , Miyuki Mukae 1 , Hitomi Fukushima 1 , Masaru Yamagata 1 , Satomi Haruki 1 , Kaoru Yokoyama 1 , Miwa Sada 1 , Mitsuhiro Kida 2 1Department of Gastroenterology, Kitasato University East Hospital, Sagamihara, Japan 2Department of Endoscopy, Kitasato University East Hospital, Sagamihara, Japan Keyword: 潰瘍性大腸炎 , 初期病変 , 鑑別診断 pp.1505-1513
Published Date 2009/9/25
DOI https://doi.org/10.11477/mf.1403101751
  • Abstract
  • Look Inside
  • Reference
  • Cited by

 The objective of this study was to clarify the endoscopic characteristics of early lesions of ulcerative colitis(UC). Among patients with UC treated at our hospital during the past 18 years, colonic lesions were evaluated by colonoscopy two or more times in 484 patients. We studied 14(2.9%)of these patients who had abnormal findings considered to be early lesions of UC. Abnormal findings were detected before the diagnosis of UC in 8 patients(early disease group)and after the diagnosis of UC but before the proximal spread of lesions in 6 patients(progressive disease group). In the early disease group, 6 patients had rectal lesions, associated with lymphoid follicular hyperplasia and aphthoid or irregularly shaped erosions. Histopathological examination of biopsy specimens obtained from affected areas showed that many patients had localized inflammation and lymphoid follicles. In the progressive disease group, 5 patients had aphthoid or irregularly shaped erosions. Our results suggested that early lesions of UC are characterized by lymphoid follicular hyperplasia and small erosions. In particular, such lesions arising in the rectum may progress to typical lesions of UC. Follow-up colonoscopic examinations are therefore essential.


Copyright © 2009, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

関連文献

もっと見る

文献を共有