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Systemic Non-Hodgkin Lymphoma Initially Presented with Visual Disturbance due to Intrasellar Lymphoma : A Case Report Soushi OKAMOTO 1 , Masanori KURIMOTO 1 , Yutaka HIRASHIMA 1 , Nakamasa HAYASHI 1 , Naoya KUWAYAMA 1 , Shunro ENDO 1 , Eikichi OKADA 2 , Shin ISHIZAWA 2 1Department of Neurosurgery, Toyama Medical and Pharmaceutical University 2Department of Pathology, Toyama Medical and Pharmaceutical University Keyword: CNS Lymphoma , systemic Non-Hodgkin Lymphoma pp.59-63
Published Date 2001/1/10
DOI https://doi.org/10.11477/mf.1436901999
  • Abstract
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A case with systemic non-Hodgkin lymphoma involving the sella turcica and kidney is reported. A 69- year-old man presented with a progressive two month history of visual disturbance and headache. Neurol- ogical examination revealed bilateral visual disturbance and right optic atrophy. MRI showed a contrast- enhancing mass in the sella turcica. The tumor extended to the right optic nerve. Without extensive studies for systemic disease, the patient immediately underwent transsphenoidal surgery. The slightly firm, fibrous and vascular-rich tumor was subtotally removed. Thehistopathological examination revealed a malignantlymphoma, diffuse-large-cell type with B-cell phenotype. The postoperative course was uneventful and thepatient's symptoms subsided gradually. The patient received radiation therapy and the tumor disappeared.Postoperative CT examinations of the abdomen and pelvis revealed a large mass at the upper portion ofthe left kidney. Ga-scan also suggested the mass to be consistent with the abdominal CT. However, the pa-tient suddenly died of acute heart failure with unknown cause just before starting chemotherapy for syste-mic lymphoma.

Patients presenting primary central nervous system lymphoma (PCNSL) may have systemic non-Hodg-kin lymphoma. To exclude systemic non-Hodgkin lymphoma, systemic investigation is essential for the ini-tial management of patients presenting PCNSL.


Copyright © 2001, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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