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Neurological Surgery No Shinkei Geka Volume 32, Issue 11 （November 2004）

Neurological Surgery 脳神経外科 32巻11号（2004年11月発行）

Japanese English

症例

Lipomatous髄膜腫の1例 A Case of Lipomatous Meningioma 小野恭裕 ¹ , 浜崎周次 ² , 市川智継 ¹ , 伊達勲 ¹ Yasuhiro ONO ¹ , Shuji HAMAZAKI ² , Tomotsugu ICHIKAWA ¹ , Isao DATE ¹ ¹岡山大学大学院医歯学総合研究科神経病態外科学 ²岡山大学附属病院病理部 ¹Department of Neurological Surgery,Okayama University Graduate School of Medicine and Dentistry ²Department of Pathology,Okayama University Graduate School of Medicine and Dentistry キーワード： lipomatous , meningioma , immunostaining , EMA Keyword: lipomatous , meningioma , immunostaining , EMA pp.1167-1171

発行日 2004年11月1日 Published Date 2004/11/1

DOI https://doi.org/10.11477/mf.1436100509

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Abstract 文献概要
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　Ⅰ．はじめに

　髄膜腫は比較的頻度の高い脳腫瘍であるが，その中で比較的稀な脂肪組織様変化を伴ったlipomatous髄膜腫をわれわれは経験した．特徴的な画像および組織所見を提示し，渉猟し得た症例の文献的考察を加えて報告する．

　We present a case of a 55-year-old woman with intracranial lipomatous meningioma attached to the left sphenoid ridge. A CT showed a mass lesion partially with a hypodensity area in the left fronto-temporal lobe. On MRI,the mass lesion contained a hyperintensity portion on T1 weighted images,which changed to hypointensity on fat-suppressed-T1 images. Histological examinations demonstrated a transitional meningioma containing lipomatous portions. Immunohistochemical studies showed negative reactivity for epithelial membrane antigen (EMA) and positive reactivity for vimentin and S-100 in the areas with lipomaous foci. This pattern of reactivity was different from that of lipomatous meningiomas reported previously. Further examinations are needed concerning the origin of tumor cells in lipomatous meningiomas.