Japanese

Ulcerative Colitis in Childhood, Report of a Case S. Kobayashi 1 , M. Nishizawa 1 , K. Nomoto 2 , A. Kariya 2 , M. Hayashi 2 11st Dept. of Int. Med., University of Chiiba pp.807-811
Published Date 1973/6/25
DOI https://doi.org/10.11477/mf.1403108559
  • Abstract
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 Ulcerative colitis in childhood is a rare disease in Japan. A child with ulcerative colitis who was studied over a year and a half is described.

 A 11-years-old male child was admitted to Chiba University Hospital in July 1971 because of bloody stool. One year previously he had begun to have episodes of bloody stool without diarrhoea. He was treated conservatively in other hospital, but his symptom was not improved.

 He was referred to our hospital because of this puzzling picture. On admission, physical examination was entirely normal except for mild moon face and moderate tenderness at the right lower quadrant.

 He was having 2 or 3 bowel movements a day. Laboratory findings included a red blood cell count of 3,950,000 and a hemoglobin of 8.6 g per 100 ml. Stools were positive for occult blood and blood sedimentation rate was 25 mm per hour.

 Barium enema showed abnormal barium coating, fein spiculations along the margin of the colon, irregularshaped niches and disappearance of network pattern of the mucosa. Absent vessel pattern, numerous bleeding spots and some erosions were recognized in the endoscopic examination. Biopsy specimens revealed crypt abscess, infiltration of inflammatory cells, atrophy of the gland of Lieberkuhn and fibrosis in the submucosal layer.

 He was diagnosed as ulcerative colitis and enema of corticosteroids was then begun. He responded well to treatment and his symptom disappeared within a few weeks. Salazopyrin was administrated after cessation of corticosteroid therapy. He has been asymptomatic for the past 12 months.


Copyright © 1973, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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