化学療法が著効を示した胃悪性リンパ腫の1例

Gastric Malignant Lymphoma Which Well Responded to Chemotherapy

　全身性の悪性リンパ腫に対する化学療法は近年好成績を上げているが，胃悪性リンパ腫は，その多くが手術療法の対象となるため，化学療法に対する報告が少なく，化学療法の効果も全身性悪性リンパ腫ほど明らかではない．今回，われわれは胃悪性リンパ腫にVincristine，Endoxan，Predonineの化学療法を行い，X線，内視鏡的に著効を示した1例を経験したので報告する．

　The patient was a 63-year-old femal with complaints of epigastralgia, abdominal mass and lt-cervical lymphadenopathy. The first x-ray and endoscopic examinations revealed multiple, deep and irregular depression surrounded by elevations with a smooth surface. From these findings and biopsy specimens of lt-cervical lymph node and the stomach, the clinical diagnosis was determined as malignant lymphoma. The chemotherapy (Vincristine 1mg/W, Endoxan 100mg/day, Predonine 40mg/day) was performed, beeing very effective. Within only two to three Weeks, abdominal mass and lt-cervical lymphadenopathy disappeared. The change of the gastric lesions were observed by the series of x-ray and endoscopic examinations. At one month after treatment, depressions had become smaller, and small and irregular erosions and ganulations of various sizes were seen. Furthermore, afteer three months, only irregular redness with or without converging folds were observed endoscopically. At this stage, endoscopic findings did not reveal malignant lymphoma.