Growth Patterns and Macroscopic Features of Colorectal Cancer Tohru Igari 1 1Department of Pathology, Tokyo Metropolitan Komagome Hospital Keyword: 大腸癌 , 肉眼形態 , 浸潤様式 , 深達度診断 pp.1199-1207
Published Date 1993/10/25
DOI https://doi.org/10.11477/mf.1403106287
  • Abstract
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 We evaluated the size, histological type, location, and shape of the surgically removed 1,592 colorectal cancers in regards to invasivity. Poorly differentiated carcinomas (por. muc. sig.) were relatively rare, but had marked invasiveness. The early cancer in the lower rectum was larger (about 3 cm) than that in any other part of the colon (2 cm). Nearly round-shaped lesions showed a tendency to have more invasive growth pattern.

 The macroscopic and microscopic findings of 144 1esions less than 3 cm in size were analyzed. We found that the macroscopic classification of colorectal cancer was not useful to estimate invasivity. We focused on the following three elements of the macroscopic findings; texture and shape of the elevation, depth of the depression, and feature of the neighboring mucosa. An elevation without superficial fine texture suggested deep invasion. A depression indicated the existence of submucosal invasion, and a deep (absolute) depression was seen when invasion reached the proper muscle layer. An elevation of the neighboring mucosa and fixed folds might appear depending on the extent of invasion. The three elements of the macroscopic findings, which described as above, seem to be useful for evaluating the extent of invasion.

Copyright © 1993, Igaku-Shoin Ltd. All rights reserved.


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