Pathological Diagnosis Macroscopically Atypical Crohn's Disease of the Colon and Rectum Hidenobu Watanabe 1 , Tamaki Ohta 1 , Yoichi Ajioka 1 , Yasushi Endo 1 1The First Department of Pathology, School of Medicine, Niigata University Keyword: 大腸Crohn病 , 非典型例 , 帯状粘膜萎縮帯 , 炎症性ポリポーシス , 病理診断 pp.447-455
Published Date 1994/4/25
DOI https://doi.org/10.11477/mf.1403105776
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 We studied on pathological diagnosis of macroscopically atypical Crohn's disease of the colon and rectum, using 41 intestinal Crohn's disease first resected surgitally.

 Typical macroscopic type of colorectal Crohn's disease was defind here as longitudinal ulcers with cohblestone and/or inflammatory polyposis (17 lesions in 41 cases), or cobblestone appearance (+inflammatory polyposis) (19 lesions), or aphthoid ulcers predominantly arranged along the colonic teniae in the edematous mucosa (early stage of Crohn's disease, No cases in this study).

 Atypical gross type was a circular irregular ulcer (or a circular atrophic mucosa) with cobblestone appearance and/or inflammatory polyposis (5 lesions) or inflammatory polyposis (3 lesions). In addition, there could be seen atypical gross findings, such as redcolored mucosa, rough-surfaced mucosa and so on.

 All of the atypical lesions had active and/or healed longitudinal ulcers in the lesion or at the periphery of the lesion, and non-caseating epithelioid cell granulomas typical of Crohn's disease.

 The macroscopically atypical findings were caused by preoperative internal medication, secondary mucosal infection, multifocal submucosal abscesses, ischemic change, and secondary change by stenosis.

Copyright © 1994, Igaku-Shoin Ltd. All rights reserved.


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