Long-term Clinical Course in Crohn's Disease of Aphthous Type Takayuki Matsumoto 1,2 , Mitsuo Iida 3 1Department of Endoscopic Diagnostics and Therapeutics, Kyushu University Hospital 3Division of Gastroenterology, Department of Medicine, Kawasaki Medical School Keyword: Crohn病 , アフタ様病変 , 長期経過 pp.1267-1276
Published Date 1999/9/25
DOI https://doi.org/10.11477/mf.1403102821
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 Radiographic and endoscopic findings of five patients with Crohn's disease of aphthous type who were observed for more than 10 years were retrospectively analyzed. Typical findings compatible with Crohn's disease developed in three patients, whereas the remaining patients were free from such findings. Time duration from initial diagnosis until confirmation of the findings ranged from 29 to 39 months. While one of the former three patients was operated on because of severe ileal stenosis, Crohn's disease in the other two patients remained inactive even though no specific treatment was administered. In the two patients without typical Crohn's disease, disappearance and recurrence of the aphthous lesions was able to be confirmed. These findings suggest that the clinical course of Crohn's disease of aphthous type is not uniform, and that this peculiar form of the disease possibly includes a subtype which does not progress aggressively.

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