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Malignant Granular Cell Tumor of the Esophagus, Report of a Case Hiroaki Iwase 1 , Kimitomo Morise 1 , Yoh Horiuchi 1 , Hirofumi Nagai 2 , Masayuki Itabashi 4 1The First Department of Internal Medicine, Nagoya University School of Medicine 2Pathology Division, National Cancer Center Resarch Institute Keyword: 食道顆粒細胞腫 pp.661-668
Published Date 1991/6/25
DOI https://doi.org/10.11477/mf.1403102561
  • Abstract
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 A 44-year-old male was admitted to our hospital because of the necessity of further examination of an esophageal polyp. He had undergone annual mass survey for stomach cancer revealing no abnormality until 1989, when a polypoid lesion was found in the lower esophagus. Esophagoscopy revealed a sweetcorn-like lesion in the lower esophagus and biopsy specimens exhibited features of granular cell tumor. Endoscopic polypectomy was performed. The surface of the resected tumor, 2.0×1.8×1.0 cm in size, was covered by pseudoepitheliomatous hyperplastic cells. There were acidophilic granules in tumor cells, some of which were atypical microscopically. Immunohistochemically, the tumor cells were positive for S-100 protein. Follow-up endoscopy perfomed 3 months later revealed a recurrent tumor in the same region. Because of the biopsy findings indicative of malignancy, esophageal resection was carried out. Review was made on 4 cases of malignant granular cell tumor of the esophagus, including the one presented here, reported to date in Japan.


Copyright © 1991, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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