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Neurological Surgery No Shinkei Geka Volume 38, Issue 5 （May 2010）

Neurological Surgery 脳神経外科 38巻5号（2010年5月発行）

Japanese English

研究

当施設における頚動脈内膜剝離術後10年の長期予後 A Japanese Hospital Reports Long-term Survival for 10 Years after Carotid Endarterectomy 芳賀整 ¹ , 卯田健 ² , 河野健一 ¹ , 森恩 ¹ , 宇賀愛 ¹ , 濱田康宏 ¹ , 矢坂正弘 ³ , 岡田靖 ³ , 詠田眞治 ¹ Sei HAGA ¹ , Ken UDA ² , Kenichi KONO ¹ , Megumu MORI ¹ , Ai UKA ¹ , Yasuhiro HAMADA ¹ , Masahiro YASAKA ³ , Yasushi OKADA ³ , Shinji NAGATA ¹ ¹国立病院機構九州医療センター脳血管センター・臨床研究部脳神経外科 ²うだ脳神経外科クリニック ³国立病院機構九州医療センター脳血管センター・臨床研究部脳血管内科 ¹Department of Neurosurgery,Clinical Research Institute,National Hospital Organization Kyushu Medical Center ²Uda Neurosurgical Clinic ³Department of Neurosurgery Cerebrovascular Disease,National Hospital Organization Kyushu Medical Center キーワード： CEA , long-term survival Keyword: CEA , long-term survival pp.437-440

発行日 2010年5月10日 Published Date 2010/5/10

DOI https://doi.org/10.11477/mf.1436101165

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Abstract 文献概要
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Ⅰ．はじめに

　欧米の大規模無作為試験^1,7)から内頚動脈高度狭窄に対する頚動脈内膜剝離術（CEA：carotid endarterectomy）の脳梗塞予防効果は確立されており，長期効果も良好と考えられている．今回，頚動脈狭窄は全身の動脈硬化の一部分症であることも鑑み，本邦当施設におけるCEA術後10年の長期予後を検討した．

　BACKGROUND: Several reports in Western countries have demonstrated the net benefit and an acceptable long-term survival of carotid endarterectomy (CEA) for severe carotid stenosis. However,long-term follow-up after CEA for carotid stenosis is not well-documented in Japan. The aim of this study was to determine long-term outcomes of CEA in our hospital.

　METHODS: 38 consecutive patients underwent 42 CEAs at the Kyushu Medical Center between May, 1994 and December, 1998. Survival follow-up was conducted in December 2008 and the incidence of late stroke was investigated in all surviving patients.

　RESULTS: A total of 37 CEAs in 30 patients (83.3%) were registered. There were 28 males and 2 females, 25 symptomatc and 5 years asymptomatic, mean ages 68+/-7 years. Survival rate after CEA was 80.0% after 5 and 53.3% after 10-years, respectively. The 10 year survival ratio free from cerebral infarction was 36.7%.

　CONCLUSIONS: For the patients in this study,CEA is associated with an acceptable long-term survival as well as a satisfactory benefical effect in stroke prevention.