乳頭上に生じた巨大な網膜細動脈瘤に対しベバシズマブ硝子体注射が奏効した2例

Intravitreal bevacizumab was effective in two cases of arterial macroaneurysm on the optic disc

要約　目的：硝子体出血で発見された乳頭上の巨大な網膜細動脈瘤にベバシズマブの硝子体内注射が奏効した2症例の報告。症例：症例はいずれも男性で，年齢は77歳と90歳である。両症例とも硝子体出血で受診した。硝子体手術が行われ，術中に乳頭上の巨大な網膜細動脈瘤が発見された。1例では黄斑に及ぶ網膜下出血，他の1例では硝子体出血の再発を繰り返した。両症例にベバシズマブの硝子体注射を行った。両症例とも網膜細動脈瘤が退縮し，再出血はなく，それぞれ0.8と0.5の最終視力を得た。結論：硝子体出血を伴う乳頭上の巨大な網膜細動脈瘤には，ベバシズマブの硝子体注射が奏効することがある。

Abstract.　Purpose：To report two cases of arterial macroaneurysm on the optic disc that cured after intravitreal bevacizumab. Cases：Both were males and were aged 77 and 90 years respectively. Both cases were referred to us for vitreous hemorrhage. Giant arterial macroaneurysm was detected on the optic disc during vitrectomy in both cases. One case showed subretinal hemorrhage involving the macula. The other case showed repeated recurrences of vitreous hemorrhage after surgery. The arterial macroaneurysm regressed after intravitreal bevacizumab in both cases with final visual acuity of 0.8 and 0.5 respectively. Conclusion：These cases illustrate that intravitreal injection of bevacizumab may be effective for arterial macroaneurysm on the optic disc.