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Japanese

Effectiveness of Kampo Medicine Gorei-san for Chronic Subdural Hematoma Mitsusuke MIYAGAMI 1,2 , Yukihide KAGAWA 1 1Department of Neurosurgery,Sonoda Daiichi Hospital 2Takenotsuka Noshinkei Rehabilitation Hospital Keyword: chronic subdural hematoma , Kampo medicine , Gorei-san , conservative treatment , CT pp.765-770
Published Date 2009/8/10
DOI https://doi.org/10.11477/mf.1436100993
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 Chronic subdural hematomas (CSDHs) are basically treated by surgery. In some cases with no or minimum symptoms, however, they may be treated conservatively. In the present study, we evaluated the therapeutic effect of a Kampo medicine (Japanese traditional herbal medicine), Gorei-san, in the treatment of those CSDHs. Gorei-san 7.5g t.i.d. was orally administered for 4 weeks in 22 patients with 27 CSDHs. Maximum thickness of the hematoma was followed up on CT scan for 4 to 29 weeks after administration of Gorei-san. In 7 of 22 patients, tranexamic acid and/or carbazochrome sodium sulfonate were also administrated.

 Gorei-san was effective in 23 of 27 CSDHs. In 12 of them, the hematoma was completely disappeared within 14 weeks after administration. In the other 11 CSDHs, the thickness was decreased. In those effective cases, thickness began to decrease 3 to 4 weeks after administration of Gorei-san. It was more effective in CSDHs with iso-/high or mixed density than with low density on CT. It was not effective in 4 out of 27 CSDHs. No apparent adverse effect was noted in the present series of patients.

 The present study suggests that a Kampo medicine, Gorei-san, is a useful option in the conservative treatment of CSDHs with no or minimum symptoms.


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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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