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Acute necrotizing encephalopathy of childhood Masashi MIZUGUCHI 1 1Department of Pediatrics, Jichi Medical School Keyword: 急性脳症 , ウイルス感染 , 視床 , 脳血管関門 pp.68-74
Published Date 1999/2/10
DOI https://doi.org/10.11477/mf.1431901026
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This paper describes the clinical, radiological and pathological features of acute necrotizing encephalopathy of childhood (ANE), a novel type of acute encephalopathy prevalent in infants and young children in the East Asia. The onset of ANE follows a febrile viral infection such as influenza and exanthem subitum, after an interval of 0.5-3 days. The prominent neurological signs at the acute stage are convulsions and coma. Laboratory examina-tions reveal in most cases liver dysfunction and increased cerebrospinal fluid protein. There are no findings suggestive of a mitochondrial disorder.


Copyright © 1999, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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