雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Changes in circumpapillary retinal nerve fiber thickness in optic neuritis positive for anti-aquaporin-4 autoantibody Yukiho Kondo 1 , Tadayuki Nishide 1 , Eiichi Nomura 1 , Ayaka Kondo 1 , Yasutsugu Ida 1 , Akiyo Kato 1 , Ai Kato 1 , Tomoyo Nomura 1 , Nobuhisa Mizuki 1 1Department of Ophthalmology, Yokohama City University Hospital pp.1273-1276
Published Date 2018/9/15
DOI https://doi.org/10.11477/mf.1410212820
  • Abstract
  • Look Inside
  • Reference

Abstract Purpose:To report changes in circumpapillary retinal nerve fiber thickness in optic neuritis in cases positive and negative for anti-aquaporin-4 autoantibody.

Cases and Method:This retrospective study was made on 27 eyes of 24 cases with optic neuritis. The series comprised 6 male and 21 female eyes. The age averaged 53 years. Anti-aquaporin-4 autoantibody was positive in 6 eyes and negative in 21 eyes. The cases were evaluated regarding visual acuity and circumpapillary retinal nerve fiber thickness for 6 months after start of treatment.

Results:Circumpapillary retinal nerve fiber thickness started to decrease 2 weeks after start of treatment in eyes positive for anti-aquaporin-4 autoantibody. The decrease was significantly greater than in autoantibody-negative ones. Visual acuity improved throughout the course of treatment up to 6 months after start of treatment. There was no difference between autoantibody-positive and -negative eyes.

Conclusion:Decrease in circumpapillary retinal nerve fiber thickness in optic neuritis was greater in eyes positive for anti-aquaporin-4 autoantibody than in negative ones.


Copyright © 2018, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

関連文献

もっと見る

文献を共有