雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

A case of hypereosinophilic endomyocarditis showing benign clinical course:A case report and review of 25 cases of this syndrome in Japan Takeshi Ishide 1 , Masahiko Shimizu 1 , Akira Nakayama 1 , Toshihiro Saito 1 , Yoshiaki Inagaki 1 , Akio Sugibayashi 2 , Morie Sekiguchi 3 1The 3rd Department of Internal Medicine, Chiba University School of Medicine 2Department of Internal Medicine, Narashino National Hospital 3Heart Institute of Japan, Tokyo Women's Medical College pp.473-477
Published Date 1985/3/15
DOI https://doi.org/10.11477/mf.1404204645
  • Abstract
  • Look Inside

A case of hypereosinophilic endomyocarditis ad-mitted to our hospital will be reported here with concomitant review of the literatures on 25 cases of this syndrome in Japan.

This is a 37 year old man who had been com-pletely well until November 1978, when he devel-oped confusion and abdominal pain. His ECG revealed T wave inversions in the limb and precor-dial leads and chest x-rays disclosed remarkable cardiomegaly and pulmonary congestion. The echo-cardiogram showed moderate pericardial effusion. Blood chemistry revealed the elevation of CPK and LDH levels and hematology showed leukocytosis and eosinophilia of 5,000/mm3 without abnormal blood cells. The stool examination revealed no parasites and related ovi. All immunological tests were nega-tive except for the scratch test of toxocara canis. No other test results were contributory to the cause of the disease.

The hypereosinophilia was spontaneously norma-lized and the patient recovered without any specific therapy. Four and a half years later, his hematology revealed no abnormalities. Hemodynamic evalua-tion including cardiac output by echocardiogram, left ventricular ejection fraction by RI method and STI were all within normal limits. Cardiac catherization with myocardial biopsy revealed normal intracardiac pressure profiles, endocardial fibrosis and hypertrophy of the working myocardium without thrombosis or eosinophilic mainfestations. His clinical course has been entirely benign.

Review of the literatures on 25 cases of this syn-drome in Japan indicates that many of the patients usually die of congestive heart failure and there seems to be no effective treatment established yet.


Copyright © 1985, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

関連文献

もっと見る

文献を共有