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Diagnosis and Endoscopic Treatment of Duodenal Neuroendocrine Tumors Satoru Nonaka 1 , Ichiro Oda 1 , Hirokazu Taniguchi 2 , Seiichiro Abe 1 , Haruhisa Suzuki 1 , Shigetaka Yoshinaga 1 , Yutaka Saito 1 1Endoscopy Division, National Cancer Center Hospital, Tokyo 2Pathology Division, National Cancer Center Hospital, Tokyo Keyword: 十二指腸 , NET , 内視鏡的切除 pp.1579-1586
Published Date 2018/11/25
DOI https://doi.org/10.11477/mf.1403201513
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 The gastrointestinal tract is the most common site for NETs(neuroendocrine tumors). Duodenal NETs are rare and occur less frequently compared with rectal NETs. In the most recent World Health Organization classification(modified in 2010), a grading system was implemented for histopathological findings of the Ki-67 labeling index and mitotic count ; then, the traditional carcinoid tumor corresponded to NET G1(partly G2). NET is usually recognized as an elevation in submucosal tumors despite being an epithelial tumor with a delle or ulceration on the tumor surface. ER(endoscopic resection)was regarded as the investigational treatment because of insfficient. However, ER has the potential to cure T1 duodenal NETs ≦1cm in size invading the submucosal layer owing to a low frequency of lymph node and distant metastasis. Indications for ER are limited ; therefore, early detection and centralization of care are important as future prospects to make sufficient evidence.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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