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Pathological Diagnosis of Duodenal Lesions:Non-ampullary Lesions without Adenoma or Carcinoma but with Ampullary Neoplasms Kazuyuki Ishida 1 , Makoto Eizuka 1 , Yoshihito Tanaka 1 , Ayaka Sato 1 , Ryo Sugimoto 1 , Yasuko Fujita 1 , Mitsumasa Osakabe 1 , Noriyuki Uesugi 1 , Yosuke Toya 2 , Syunichi Yanai 2 , Shuhei Oana 2 , Shotaro Nakamura 2 , Takayuki Matsumoto 2 , Tamotsu Sugai 1 1Department of Molecular Diagnostic Pathology, Iwate Medical University, Morioka, Japan 2Division of Gastroenterology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan Keyword: 非乳頭部十二指腸病変 , 限局性病変 , びまん性病変 , 乳頭部癌 , 病理組織学的所見 pp.1563-1578
Published Date 2018/11/25
DOI https://doi.org/10.11477/mf.1403201512
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 Here we present a pathological diagnosis of non-ampullary duodenal lesions without adenoma or carcinoma, and ampullary neoplasms. Among elevated duodenal lesions, it is difficult to endoscopically distinguish between neoplastic lesions and non-neoplastic lesions, such as those associated with heterotopic gastric mucosa, Brunner's gland hyperplasia, and hamartoma. Diffuse duodenal lesions are often non-neoplastic and are components of systemic disease. Pathological entities and diagnostic clues related to duodenal lesions without adenoma or carcinoma have been standardized and should be understood. On the other hand, indications for the endoscopic management of ampullary lesions have increased. Effective clinical strategies for treatment of ampullary carcinoma are particularly important.Further research is needed to generate clinicopathological and molecular biological findings to improve clinical strategies for the management of ampullary carcinoma.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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