雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Gastric Carcinoma of Superficial Spreading Type with Partial Adenoacanthoma N. Kuwabara 1 , S. Watanabe 1 , Y. Fukuda 1 , K. Sakai 2 , M. Tsuchidate 2 1The Dept. of Pathology, Juntendo University, School of Medicine 2The Dept. of Surgery, Kawaguchi-Saisei-kai Hospital. pp.253-257
Published Date 1975/2/25
DOI https://doi.org/10.11477/mf.1403112187
  • Abstract
  • Look Inside

 It is well-known that primary adenoacanthoma of the stomach is a rare disease, and fifty-eight case reported since Rösing (1895) were all “advanced carcinoma”.

 Our present case shows primary adenoacanthoma in the so-called pm. cancer with superficial spreading type.

 Case report: The patient was a 71-year-old woman and her chief complaint was swelling of the lymphnodes on both sides of her neck.

 The biopsy of the lymphnode showed “metastatic adenocarcinoma” histologically, so that she underwent an upper-gastrointestinal tract series and endoscopic examinations which revealed carcinoma lesion in the posterior wall of the gastric body region near the greater curvature (suspected Borrmann Ⅲ). She underwent laparotomy and subtotal gastrectomy.

 Pathological finding of the resected stomach:

 Grossly, it showed so-called superficial spreading type carcinoma, extending to the whole antrum, mid-body of posterior wall and ulcer formation along the greater curvature.

 Microscopically, as is shown in Fig. 3, carcinoma was composed of three different cell types, mucocellular adenocarcinoma mainly in the antrum and body regions with two small lesions of squamous cell carcinoma in the surface mucosal layer and muconodular adenocarcinoma along the greater curvature.

 Most carcinoma were found in the submucosal layer, partly extending to muscle coat.

 There was remarkable carcinoma invasion in the lymph vessels in the submucosal layer and several metastatic lymphnodes at the lesser curvature.

 Conclusion: In this case, two lesions of squamous cell carcinoma were found in the superficial mucosal layer and the carcinomatous basal cells were connecting with and changing into the mucocellular adenocarcinoma in multiple foci of deep mucosal layer.

 In addition, the epithelium surrounding the surface mucosa of squamous cell carcinoma was well-defined from the intestinal metaplasia of foveolar epithelium and atypical regeneration. For this reason, superficial epithelium cannot be considered as the origin of squamous cell carcinoma.

 It was considered that this was the undifferentiated basal cell of squamous cell carcinoma originated from mucocellular adenocarcinoma cells.


Copyright © 1975, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

関連文献

もっと見る

文献を共有