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Scirrhous Carcinoma of the Stomach Showing Rapid Growth, Report of a Case T. Kasugai 1 , H. Kishikawa 1 , H. Sugiura 1 , S. Yokoi 2 1Department of Medicine, Aichi Cancer Center Hospital 2Yokoi Clinic pp.499-503
Published Date 1974/4/25
DOI https://doi.org/10.11477/mf.1403111801
  • Abstract
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 A 53 year-old man suffering from epigastric discomfort and poor appetite visited our clinic.

 An upper gastrointestinal series was unremarkable and gastrocamera examination revealed atrophic gastritis without findings suggesting malignancy. Approximately one year after the first visit, he again visited our clinic with the complaints of urination-trouble, full sensation of the lower abdomen, constipation and lumbago.

 The second upper gastrointestinal series showed rigidity of the greater and lesser curvatures, and filling defects at the angulus and in the greater curvature of the lower body of the stomach.

 The second gastrocamera examination done one year later revealed thickening and rigidity of the gastric mucosa, and irregularly nodular, swollen mucosal folds partially with small masses on the anterior and posterior walls, and the greater curvature in the mid-and lower body. An irregularly shaped, shallow ulcer was also visualized on the lesser curvature of the lower body of the stomach. A diagnosis of gastric carcinoma of Borrmann type Ⅳ was made.

 Gastric biopsy under direct vision demonstrated adenocarcinoma tissue with a number of signet-ring cells.

 Operation could not be performed because of peritoneal carcinomatosis with ascites. He died 4 months after his admission, despite chemotherapy.

 Two sisters of his were also affected with gastric carcinoma nearly at the same time.

 The one had an inoperable gastric cancer of Borrmann type Ⅳ associated with carcinomatous peritonitis, and the other had an early gastric cancer of type Ⅱc which was successfully treated surgically. Histologically those lesions demonstrated adenocarcinoma with signet-ring cells as was also the case with their brother.


Copyright © 1974, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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