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A Case of Gastrointestinal Polyposis with Protein Loss: gastric polyposis, duodenal polyp and rectal polyp J. Naramoto 1 , H. Taketomi 1 , M. Morimatsu 3 1Iizuka Doctors Association Medical Center 32nd Dept. of Path., School of Med., Kurume Univ pp.1575-1579
Published Date 1971/11/25
DOI https://doi.org/10.11477/mf.1403111454
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 This report concerns with gastrointestinal poIyposis, gastric protein loss, hypoproteinemia and anemia found in a 34-year-old male patient who improved after total gastrectomy.

 Gastrointestinal series disclosed multiple polyposis of the stomach, single duodenal and rectal polyps. lnitital laboratory studies revealed hypoproteinemia and anemia. Total serum protein level was as low as 5.0g/dl. Hemoglobin was 50% (Sahli). Intravenous RISA test revealed hypercatabolism of serum protein with resultant loss into the gastric juice. RISA half life was shortened to 4.5 days. 131I-radioactivity was significantly found in the gastric juice. Gastric hypersecretion and hyperacidity were shown by augmented histamin test. Hepatic and renal functions were normal.

 The patient was diagnosed as a case of protein-losing gastro (entero) pathy and total gastrectomy was performed (esophago-jejunostomy). Soon after the operation he suffered from serum hepatitis, but improved two months later. Serum protein level rose up to 7.0~7.6 g/dl two months after operation.

 Improvement of hypoproteinemia and anemia has continued.

 In the resectecl stomach showing multiple polyposis, microscopic findings revealed proliferation and cystic dilatation of the gastric pits. Edema, inflammatory cell infiltration and enlargement of lymph vessels were also noted in the lamina propriae mucosae.


Copyright © 1971, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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