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Two Cases of Localized Lymphoreticular Hyperplasia of the Stomach J. Naramoto 1 , H. Taketomi 1 , Y. Akaike 1 , T. Shida 1 , M. Morimatsu 2 1Iizuka Doctors Association Medical Center 22 nd Dept. of Path., Kurume University pp.931-935
Published Date 1972/7/25
DOI https://doi.org/10.11477/mf.1403109206
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 The purpose of this paper is to report two cases of localized reactive Lymphoreticular hyperplasia of the stomach and compare them to the previous literature.

 Case 1: A 61 years old male had complaint of epigastric fullness, while treated for arteriosclerosis with hypertension. Upper gastrointestinal series disclosed a gastric tumor with central ulceration on the lesser curvature of the gastric corpus. Clinically, it was difficult to clarify its nature, benign or malignant. Histologically, the tumor, measuring 3.0 by 2.0 by 0.8 cm, was composed of massive lymphoid hyperplasia situated mainly in the submucosa infiltrating down to the muscular layer with relative clear-cut border. Lymphoid hyperplasia with reaction centers was found in the lesion. Infiltrating cells were composed of lymphocytes, reticulum cells and inflammatory cells without cytological malignancies. No remarkable changes were seen in the lymph nodes. There were no evidences of malignancy during fifteenth months' follow-up period.

 Case 2: A 56 years old female was admitted with an attack of eholelithiasis. Surgical treatment was recommended after clinical examinations such as liver function test, cholecystography and upper gastrointestinal series. X-ray of the stomach disclosed a gastric submucosal tumor on the anterior wall of the lower cardiac area. Cholecytectomy combined with gastrectomy was performed. Postoperative histological study of the stomach revealed the tumor, measuring 3.0 by 2.5 by 1.0 cm, composed of Lymphoreticular hyperplasia with proliferation of collagen fibers.

 There is no single criterion which helps to make accurate the differential diagnosis of malignant lymphoma and massive lymhoid hyperplasia such as in case 1. The final diagnosis may depend upon the followup study after operation.


Copyright © 1972, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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