雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Experimental and Clinical Studies on the Development of Carcinoma of the Remnant Stomach N. Kaibara 1 , H. Nishidoi 1 , S. Koga 1 , T. Sugihara 2 1The Ferst Department of Surgery, Tottori University, School of Medicine 2Department of Surgery, Hirose Hospital pp.1359-1364
Published Date 1982/12/25
DOI https://doi.org/10.11477/mf.1403108648
  • Abstract
  • Look Inside

 Gastric carcinoma was induced with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in rats that underwent partial gastrectomy removing 1/2 of the glandular stomach. Adenocarcinoma developed in the remnant stomach with the incidence being 38.9% in rats that received Billroth Ⅱ reconstruction, 25.0% in those with short Roux-Y reconstruction, 7.1% in those with long Roux-Y reconstruction and 9.5% in the control, indicating higher incidence of gastric carcinoma in rats with greater amount of duodenogastric reflux. Site of the tumor developed in the remnant stomach was on the anastomotic region. These results suggest that the reflux of duodenal juice (including bile) is substantially related to the development of chemically-induced carcinoma of the gastric remnant.

 In our series of patients with carcinoma of the gastric remnant, site of the tumor was on the stoma in 9 of 11 cases, which was in accordance with the animal model. Polypoid changes, termed histologically as gastritis cystica polyposa, are seen in the mucosa of the anastomosis and they have been interpreted as being related to carcinoma development. In the present study, a case of gastritis cystica polyposa with intramucosal carcinoma is presented.


Copyright © 1982, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

関連文献

もっと見る

文献を共有