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Clinico-pathological Studies on So-called Ulcer-cancer of the Stomach T. Yao 1 , H. Watanabe 2 12nd Dept. of Internal Medicine, Faculty of Medicine, Kyushu University 22nd Dept. of Pathlogy, Faculty of Medicine, Kyushu University pp.573-584
Published Date 1976/5/25
DOI https://doi.org/10.11477/mf.1403107232
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 A total of 132 stomachs with gastric cancers of depressed type resected surgically, were subjected to the study. The 132 cases had been clinically eximined by x-ray and/or endoscopy 2 weeks to 10 years prior to the operation. Retrospective analyses of their clinical course and histopathological findings of the resected stomachs have given us the following results.

 1) No case was observed who had primary gastric ulcer to make cancerous change.

 2) The great majority of the resected stomachs satisfying the histopathological criteria for ulcer-cancer had clinically been observed as complete or incomplete healing of peptic ulceration in the cancerous area.

 3) The commonest pathological future of ulcer-healing-cancer was cancer-cell-free dense submucosal fibrosis at and far from the advancing margin of the canter.

 4) Growing rate of gastric cancer with cancer-cell-free fibrosis was slower than that of gastric cancer without such fibrosis.

 The above-mentioned findings have led us to consider that the so-called ulcer-cancers are merely carcinomas associated with chronic peptic ulceration.

 It should also be emphasized that rate of growth gastric cancer may greatly be influenced by peptic invasion in the cancerous tissue.


Copyright © 1976, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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